Friday, November 29, 2019

Image of Filipino Women free essay sample

Like in Estrella Alfon’s Magnificence; she illustrated that Filipino women are tough when it is for her children; while Lumnay was very weak and couldn’t accept her husband’s marriage to another woman. . Filipino women could stand and hold firm on her virtues and ideals. No matter what the consequences are, they stand for what is right. Sometimes they are mocked and insulted because of their ideals. But these women, like Miss Noel stood determined to continue what she has started and what she was fighting for. Esperanza is also a woman of virtue. She despises sleeping with a man to whom you’re not married. Some Filipino women are very innocent when it comes to hardships, emotions or other things surrounding them. Majority of these women were born or they belonged to middle class family. They haven’t experienced difficulties while growing up. While some women are oblivious to difficulties and hardships, some are introduced to it a very young age. We will write a custom essay sample on Image of Filipino Women or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page They sacrificed their happiness for the sake of their family and loved ones. They think of everything as they’re responsibility and it affects their way of thinking, their social life and even their marital life. Filipino women are generous and very caring. They support their family through thick and thin. They will never let their family down especially when it comes to children. They are also very sweet and understanding, Filipinas are also very jealous, they are very possessive not only on the material things but also with their loved ones, especially the mothers.There are also this conservative God-fearing Filipinas. They have principles and won’t go against it. There are many more character traits a Filipina could have, but whatever the point is, Filipinas are raised differently and you could see it by the way they talk or move. Filipino women may look independent and wise but still, they need to feel deserve to be respected and cared for. They need to be loved and feel loved.

Monday, November 25, 2019

Life and Work of Herbert Spencer

Life and Work of Herbert Spencer Herbert Spencer was a British philosopher and sociologist who was intellectually active during the Victorian period. He was known for his contributions to evolutionary theory and for applying it outside of biology, to the fields of philosophy, psychology, and within sociology. In this work, he coined the term survival of the fittest.  In addition, he helped develop the functionalist perspective, one of the major theoretical frameworks in sociology. Early Life and Education Herbert Spencer was born in Derby, England on April 27, 1820. His father, William George Spencer, was a rebel of the times and cultivated in Herbert an anti-authoritarian attitude. George, as his father was known, was the founder of a school that used unconventional teaching methods and was a contemporary of Erasmus Darwin, grandfather of Charles. George focused Herberts early education on science, and simultaneously, he was introduced to philosophical thinking through Georges membership in the Derby Philosophical Society. His uncle, Thomas Spencer, contributed to Herberts education by instructing him in mathematics, physics, Latin, and free-trade and libertarian political thinking. During the 1830s Spencer worked as a civil engineer while the railways were being constructed throughout Britain, but also spent time writing in radical local journals. Career and Later Life Spencers career became focused on intellectual matters in 1848  when he became an editor for  The Economist, the now widely-read weekly magazine that was first published in England in 1843. While working for the magazine through 1853, Spencer also wrote his first book,  Social Statics, and published it in 1851. Titled for a concept of August Comte, in this work, Spencer used Lamarcks ideas about evolution and applied them to society, suggesting that people adapt to the social conditions of their lives. Because of this, he argued, social order would follow, and so the rule of a political state would be unnecessary. The book was considered a work of libertarian political philosophy, but also, is what makes Spencer a founding thinker of the functionalist perspective within sociology. Spencers second book,  Principles of Psychology, was published in 1855 and made the argument that natural laws govern the human mind. At about this time, Spencer began to experience significant mental health problems that limited his ability to work, interact with others, and function in society. Despite this, he began work on a major undertaking, which culminated in the nine-volume  A System of Synthetic Philosophy. In this work, Spencer elaborated on how the principle of evolution had been applied within not only biology, but in psychology, sociology, and in the study of morality. Overall, this work suggests  that societies are organisms that progress through a process of evolution similar to that experienced by living species, a concept known to as social Darwinism. In the latter period of his life, Spencer was regarded as the greatest living philosopher of the time. He was able to live off of income from the sale of his books and other writing, and his works were translated into many languages and read all over the world. However, his life took a dark turn in the 1880s, when he switched positions on many of his well-known libertarian political views. Readers lost interest in his new work and Spencer found himself lonely as many of his contemporaries died. In 1902, Spencer received a nomination for the Nobel Prize for literature, but did not win it, and died in 1903 at the age of 83 years old. He was cremated and his ashes interred opposite the grave of Karl Marx in Highgate Cemetery in London. Major Publications Social Statics: The Conditions Essential to Human Happiness (1850)Education (1854)The Principles of Psychology (1855)The Principles of Sociology (1876-1896)The Data of Ethics (1884)The Man Versus the State (1884) Updated by Nicki Lisa Cole, Ph.D.

Friday, November 22, 2019

Indicator of Business assessment on Nursing home Article

Indicator of Business assessment on Nursing home - Article Example Thus, the role of nursing homes becomes one of the top most importance in today's life of the society. The elderly care industry can be split into two categories - nursing homes and residential care homes. Nursing homes are fundamentally private hospitals for elderly residents calling for high levels of care, staffed by managers and nurses with sophisticated levels of medical and care training. Residential care homes, on the other hand, are old people's homes. They provide a place to stay for elderly people who conceivably cannot do everything for themselves, yet nevertheless enjoy a degree of independence and require little hands-on care. They are staffed by qualified care takers whose level of training need not be as advanced as those working in nursing homes. Nursing homes as a business or an investment is a field which looks healthy in spite of the economic catastrophe. There are a number of reseat developments for this friendly environment for the investors. Though the extra legislation introduced through the Care Standards Act has made it binding for the potential purchasers to prepare and make a lot of commitment financially and personally on staffing and maintenance of the nursing home, any body now planning to go into this business is assured of study income and thriving business. Running a nursing home can be a rewarding business, as the returns one get from the care homes would be very significant. The majority of nursing facility services is funded by the Medicare and Medicaid programs. Nursing homes with private care patients generally provide higher quality care than facilities dependent on Medicaid patients. National Senior Citizens Law Center states that nursing homes discriminate against Medicaid patients versus private pay. The difference may be a special wing of a home, eviction of Medicaid patients and inferior food and services. One expert noted that nine out of ten attorneys give bad advice on qualifying for Medicaid. Approximately 63% of nursing-home patients of cognitively impaired. Nursing homes provide long term and sub-acute care to persons in need of 24-hour nursing services or significant supportive services. The quality of care and quality of life for residents of nursing homes have been a concern for decades. Nursing home residents are generally frail, physically and psychosocially compromised, heavily dependent upon others for basic care and sustenance, and in some cases near the end of their lives. When residents live in an environment where they are totally dependent on others, they are especially vulnerable to abuse, neglect and exploitation. Nursing home licensees must protect these vulnerable persons and are expected to provide the necessary care and services to allow each resident to achieve and maintain his or her highest possible level of function and well being. Financial status, in fact, causes inequalities in the quality of care received by an elderly person. It mainly may not be with in the same nursing home. African Americans are four times more likely than their white counterparts to reside in substandard nursing homes. But obviously if one has got money the service he gets is simply remarkable. The Silverado is an example to it; Silverado specializes in residents with severe dementia. Most assisted-living homes quarantine such patients in separate wards or ship them off to nursing homes when their

Wednesday, November 20, 2019

TD 5- HRM - 402 Delivering Training and Development Essay

TD 5- HRM - 402 Delivering Training and Development - Essay Example This will also help the management to develop further their future training programs, including pinpointing the relevant topics or areas that are absent from the training. Level 2: Learning – Under this level, Walmart Human resource manager measures what the employees under training have learned and by how much their knowledge has increased due to the training. This level of evaluation allows the management to measure learning using the specific objectives set for the training, and this will influence their decision on whether to changes in skills, knowledge or attitude. This is beneficial to the Walmart organization as it helps them to know what the employees are learning and what they are not as this will assist them to improve future training sessions. (Clifford & Thorpe, 2007) Level 3: Behavior – On this level the management evaluates how the employees’ behavior has changed basing on training that they underwent. Behavior change translates to how much information the employees got from the training program. The Walmart management, through training, they can now provide the necessary conditions to initiate the change in their organization. (Siddons & Development, 2006) Level 4: Results – The Management analyzes the results of the training at this level. This consist of outcomes that the organization has resolute to be the best for the business, best for its employees, good for the overall Walmart

Monday, November 18, 2019

Assessment and care of a client with complex needs. Mental Health Essay

Assessment and care of a client with complex needs. Mental Health nursing] - Essay Example 15). This involves a methodical evaluation of the social and health care requirements of an individual who has been brought to the ‘specialist mental health services’ (Forster, 2001, p. 15). An important component of the CPA is the assigning of a service provider who will work with the client and his/her family or caregivers to evaluate needs, create and carry out a care plan. In the CPA service provider task, the nurse is largely involved in locating an array of assessment needs, several of which could be outside the own knowledge or capability of the nurse. Besides the troubles brought about by mental disorders, numerous clients with serious and chronic mental disorders will be further impaired by ‘secondary impairment’ (Bartlett & Sandland, 2007). This will lead to a kind of disability marked by difficulty carrying out daily tasks such as cooking, going to the grocery, using public transport, and so on. Professional assessments from service providers shou ld be requested. In nursing theory and practice, bipolar disorder is classified as one of the most complex mental health disorders. The best nursing care takes place during the acute illness stage and remission (Suppes & Dennehy, 2010). This paper presents a case study of the mental health condition of Ms. ... She eventually became tardy. Her performance at work began to deteriorate. Ms. M herself admitted that she has difficulty concentrating at work. She also said that she feels lost and lonely at times. Her sleep patterns also became abnormal. She sleeps late but wakes up very early. But, interestingly, she began to show more enthusiasm and energy in the morning. Her sister reported that Ms. M became short-tempered all of a sudden and has been, for the first time, openly expressing her desire to become a model. Ms. M was diagnosed with depression and alcohol related problems. Ms. M’s mental health condition may be caused by genetics or environmental factors. A depressive episode may take place without any clear cause. It could be that something stressful in Ms. M’s immediate environment caused the sudden changes in her behaviour; it could be a stressful event at work or at home. A medical condition can also cause episodes of depression, such as brain tumour or stroke (Vide beck, 2010). According to Boyd (2008), use of substance and consumption of alcohol may also activate symptoms of depression. Case Analysis The symptoms of Ms. M are indicative of bipolar disorder. An individual episode of abnormal and chronic irritable mood. During Ms. M’s episodes of mood disorder, the following symptoms of bipolar disorder have continued: difficulty concentrating; more conversational than normal; excessive energy and enthusiasm; abnormal sleeping patterns; and increased confidence (e.g. desire to enter modeling). The mood disorder is quite serious to cause noticeable disruption in occupational performance or in personal relationships. The symptoms may be triggered by alcohol related problems. Because bipolar disorder often includes depressive and manic episodes, knowledge of

Saturday, November 16, 2019

Cystic Fibrosis: Molecular Mechanisms and Diagnosis

Cystic Fibrosis: Molecular Mechanisms and Diagnosis Cystic fibrosis is a membrane transport disorder which is commonly affected in the autosomal recessive disease of white populations. It is also identified at birth by a certain condition called meconium ileus which means intestinal obstruction. In the advance stages, clinically it has been diagnosed by sticky viscous secretion of the pancreas and lungs (Gelehrter, 1998). Many years of direct research has failed to recognise the specific gene which is involved in cystic fibrosis (CF), although there are some various indirect research done which has indicated that there appeared an abnormality in the transport of ions during the process of cell membrane development. A very common diagnosis has been used to recognise this disease which is high increase of chloride content in sweat. Children suffering from this disorder develop pancreatic insufficiency which is usually treated with enzyme supplementation, antibiotics and physical treatments which are used to reduce the chest infection. Earlier the survival average is about 25 years. (Gelehrter, 1990). But in a recent study, it has been said that the life expectancy for cystic fibrosis patients has increased over the last 40 years. It has been necessary to identify the respiratory viruses in Cf to make the clinical decision to proceed with the necessary treatment. (cited in Wat, 2008). It is said that one can calculate approximately the frequency of heterozygous carriers would be about 1 in 25 individuals. There are various research works done on cultured cells and animal models to further study on the basic defects of the disease and find a successive treatment. (Hodson, M.E., 1995). HISTORY: From centuries the study and research of Cystic fibrosis has been done. Earlier people started diagnosing this condition in the newborns due to the salty taste in their skin. The survival rate was so low as six months. But as years followed, during the 1930s, a scientist named Guido fanconi had described the symstoms as gastrointestinal symdrone but latter named it as cystic fibrosis. The research had advanced when the cystic fibrosis gene was discovered following the study of mendels law researched by Gregor Mendel. The genetic knowledge on this particular disease was made more improving which indirectly improved the survival ascepts of CF patients. By 1980s, a deeper understanding of human genetics were developed. In 1989, two researchers had isolated the damaged gene in causing CF which was the main cause in affecting the chloride channel function. These were the channels which were helping in the movement of water and salt in the cell walls. Further study on this is making it pos sible to understand and find a treatment for this genetic disease. In recent years, various study via Gene theraphy has been helping various researches to fix the damaged gene. If this particular gene is fixed, the possible prevention, treatment and cure of CF would become a (Giddings,2009) Basic molecular genetics of Cf: In the year 1985, several groups were experimenting on gene therapy by linkage analysis, a linkage was observed on the chromosome 7, which in turn proceeded with testing some of the markers on chromosome 7 where they found CF gene near to these markers (met and J3.11). Techniques like physical mapping showed that the distance between these markers was approximately 1.6 million bp, which is as large for approximately 50 genes. Various interesting research were made in which it was found that a vast majority of chromosomes carrying the Cystic fibrosis mutation were also carrying a particular alleles for XV-2c and KM-19 which was further named as allele for XV-2c and + allele for KM-19. This type of hapotype (-/+) showed approximately in 25% of normal chromosomes, whereas rest showed other different patterns. A term was defined for this type of disease gene associated with a allele with the nearby markers, which was named as Linkage Disequilibrim. This term was made used to understand that these CF mutated genes were being descended from a common ancester. (Gelehrter, 1998) In a recent research, a genetic analysis was conducted by carefully cloning of a 500,000 bp candidate which resulted in three possible genes from the specific region which was studied. In testing under northern blotting technique it was found that this specific gene was coding for a 1480- amino acid protein including 26 exons with a length of 250,000 bp of DNA and the mRNA transcript was found to be 6129 bp long. In further studying a cloned and sequenced cDNA was prepared using the sweat glands of a Cf patient, it was found that there was a difference in exon 10 from a normal sequenced gene. There was a deletion in the 3 -bp found which might have caused the deletion of a single amino acid (phenylalanine) at the specificresidue 508. (Gelehrter, 1990). This type of mutation is known as Delta F508 or F508. Patients with homologous delta F508 mutation will tend to suffer with severe symptons of this disease, causing a very heavy loss of chloride ion transport.This causes an improper balance in the sodium and chloride ion ratio, eventually secreting a thin, mucus secretion in the lung area which traps bacteria, this causes severe lung infection, resulting a high mortality rate in CF patients. CFTR gene: This gene was initially cloned in 1989 in which it was mapped to human chromosome 7q21, with more interest in this particular region, researches were able to indentify 2 more closely linked markers other than (labelled MET and D758) which were D75122 and D75340, those were 10 kb part. Using lambda genomic DNA libraries, 280 kb of DNA were sequenced which were used to make long range restriction maps. These were also probed with cDNA clones to isolate a total of 500 kb. This can be seen in the figure By using various approaches like screening zoo blots, northern blots and cDNA libraries the genomic DNA clone was isolated. Four different regions were isolated, out of that, only one proved to be CF gene which was 6.5 kb sequence in length. Eventually, it was concluded that the CF gene controls the CFTR (cystic fibrosis transmembrane regulator) which encodes chloride channels which were responsible for the water transport on the plasma membrane of the epithelial cells which were connected to the lung airways. This mutation was causing the problem. Structure of the CFTR gene: After sequencing the CFTR gene, further study was done on it. The sequenced coding region of this gene showed a polypeptide molecular mass of 168138 daltons. The best site seen in this predicted protein was that it showed two repeated motifs, which showed some similarities to the nucleotide-binding domains (NBD) which is present in the membrane bounded protein. These membrane consisted in them six hydrophobic regions which composed 234 amino acids. Hydrophilic domains: These 2 hydrophilic domains contains approximately 150 amino acids in which some phenylalanine residue has been deleted at the region of the first NBD which shares similar homologies with the proteins which binds with the nucleotide. These two motifs are connected by a highly charged cytoplasmic domains referred as R- domain or regulatory domains. This domains encodes 13 exons that help in the phosphorylationby protein kinase K and rest helps in binding sites by protein kinase C. These domains and nucleotide binding folds in the binding sites suggest that hydrolysis is involved in the transportation of CFTR gene. CFTR Promoter: It was found out that CFTR gene had a addition promoter region with a size of 3.5 kb, later on, it led that these promoters showed the characteristics of housekeeping gene along with tissue specific functions. There were five reasons that were focused to show that the CFTR gene had these charactertics which were as follows: There were no TATA box element within the first 500 basepairs of the transcription sites. The GC content in the promoter region was high. There were addition multiple minor transcription sites identified along with the major transcription sites. Couple of SP1 sites were also identified. There was a very low expression of the CFTR gene found in the epithelium layer. Another conclusion was made that the CFTR gene might control transcription regulation. (prin mg, tho) Phenotypic function of the diseased gene: To understand the phenotype of the disease, it has been confirmed that an individual suffering must have two copies of a mutated Cystic fibrosis transmembrane conductance regulator (CFTR) gene to be expressed. It has also been understood that the development of this disease in different individuals varies due to differential influence by environmental and genetic factors. This various different forms of other genes can affect the phenotypes of the mutated gene of this disease.   MUTATED GENE: As it been understood that the most common mutated gene found in most cystic fibrosis defective gene is the delta F508. A detailed study about this gene was done in which it was found that CFTR protein helps in encoding single amino acid at position 508 on the chromosome 7. As this mutation affects the CFTR to perform its work in the cell and prevents it from locating itself in the cell membrane. Usually it is seen that, a newly synthesized CFTR protein adds itself to the missing chemical group by folding itself into appropriate shape which are escorted by their specific molecular chaperons to the surface of the cell. Because of the presence of this mutated CFTR gene, the imperfect CFTR binds onto the cell membrane which has a defect while opening and closing during regulating the chloride ion flow within the cell membrane. There are different mutated genes, in which some do not this synthesis or any modification or integratation into the membrane of the cell. Sometimes, these mutated genes fail to even respond to the signals within the cell that are responsible for the opening and closing of chloride flow. In some cases, the CFTR protein enters the cell membrane and also responds to the cell membrane but there would show a problem when the channel opens and there is improper flow of chloride ion out of the cell. Different mutations vary with different patients, patients with absent or very low CFTR protein in its cell membrane would cause severe disease causing depleting pancreatic functions. There are patients which have delta F508 mutation on both CFTR gene copies, this causes very poor pancreatic function which would secret high amount of mucus causing varying degrees of infection in the lungs. Another CFTR mutation namely R117H also develops a partial functioning CFTR protein, this mutation pairs w ith the severe mutated gene delta F508 causing the CF disease severe but varying in lung disease. It has been seen that some men who have been detected with this particular mutated gene R117H shows only one symptom of CF that is being Infertile which is due to lack of vas deferens. Inheritence of the CF gene: Diagnosing cystic fibrosis In most cases, cystic fibrosis is diagnosed by screening tests, which are carried out very early in life. However, some babies, children and even young adults have some unexplained illness in future so they are diagnosed later. There are four main ways of diagnosing cystic fibrosis: newborn testing antenatal testing carrier testing sweat testing Newborn Screening: In newborn screening there are two tests the first one is blood test in which small amount of blood is taken from the babys heel and transferred onto the card and it is examined in the laboratory for CF and it is also test inherited conditions, such as sickle cell anaemia and phenylketonuria.. Another test is genetic test in which saliva sample taken from the cheek and check whether a newborn has faulty CFTR genes. Antenatal testing: This test is done during the womens pregnancy to know that fatus has CF or not. There are following Amniocentesis: in it inserts a needle through abdominal wall into the uterus and take amniotic fluid surrounds the baby and tested in the laboratory Chorionic villus sampling: In it needle passed through the stomach into the womb sometimes a fine tube passed through the vagina into the neck of the uterus as an alternative. And take chorionic tissue which is a tiny piece of the developing placenta and these chromosomes which are in the cells of the tissue are examined in the laboratory for CFTR genes are normal or not. Both tests have risk of complication and also chance for miscarriage so it is offered only those mothers who have high risk of having child with the CF. Carrier testing: People who have two CFTR genes one is normal and another is faulty are CF carriers. So carriers pass faulty CFTR genes on to their children. This is simple test which is uses mouthwash to make sure that person is a carrier of cystic fibrosis. Swishing the mouthwash to collect the cells. And these containing cells are checked for the faulty gene. Sweat test: If blood and genetic tests have positive sign for CF so for confirmation sweat test diagnosis using This test measure the amount of salt in sweat. For that in one treatment room small area of skin on an arm or leg tested. Rub this skin with sweat producing chemical and then produce gentle electrical current with help of electrode it gives warm feeling .collect sweat on a pad or paper for analze. High levels of salt confirm diagnosis of CF. (180,205) Immunoreactive Trypsinogn: This analysis is used after sweat test if little sweat measured in newborns. Blood samples are taken after 2-3 days of birth and examined for immunoreactive trypsinogen (IRT) which is the increased levels of pancreatic enzyme. If IRT level is high then also it is not strong indicator of CF. Because infants with intestinal malformations and condition as bowel obstruction also have high level of enzyme which is for function of impair pancreatic. Lung X-rays and function tests: In the tests measure the amount of air the lungs can hold and how fast a person can breathe out to show how lungs add oxygen and remove carbon dioxide from the blood with the help of chest X-ray which show lung scarring from recurrent inflammation.This test do not confirm a diagnosis of CF but help in evaluating the severity of an individuals lung damage. Sinus X-ray: This test give signs of sinusitis, which indicates an infection and inflammation of nasal cavities. The X-ray shows the underlying cause becomes important for sinusitis. By cause of sinusitis is showing allergies and poorly functioning immune system. DNA mutation analysis: For highly specific result we used this technique for CF to look for the presence of many mutations in the CFTR gene. In it DNA isolated and purified from the blood sample or from a smear inside the cheek and for detect disease genes and indentify mutation within a specific DNA sequenced used micro array technology Sputum cultures: For this test, take a sample of your sputum (spit) to see what bacteria are growing in it. If there are bacteria called mucoid Pseudomonas, then it is advanced CF that needs aggressive treatment. (Giddings, 2009) TREATMENT In early years, there were no proper complete cure for cystic fibrosis . This has changed in recent years due to various researches done to treat CF which have been improved drastically. The aim for the treatment of cystic fibrosis are to Prevent infection in lungs,Remove the thick and sticky mucus from lungs, Prevent blockages in intestines and to Provide adequate nutrition.(http://www.nhlbi.nihHYPERLINK http://www.nhlbi.nih.gov/.gov/) Treatment for lung problems: It is essential to begin the treatment by reducing the infection and removing the thick and sticky mucus from the lungs. This can be done by performing the following lung treatment methods. CHEST PHYSICAL THERAPHY (CPT): This theraphy is also called percussion. CPT include pounding the chest and back over and over with the hands and a device that reduce the mucus layer from the lungs. Breathing techniques are also helpful to remove mucus from lungs. This techniques involve forcing out of some short or deeper breaths and following with a relaxed breath. The major purpose of this therapy for CF is to increase clearance of mucus and control infection in the lung and also to provide adequate nutrition and prevent intestinal blockage. MEDICINES: This is the primary treatment for the cystic fibrosis. Using medicines it helps in treating lung infection, decreases the swelling ,reduces the mucus and also opens the airways. The following types are the antibiotics used for cystic fibrosis treatment: Oral antibiotics are use to treat the lung infection. Inhaled antibiotics are used to control the infection caused by the pseudomonas bacteria. Intravenous medicines are used for control the severe infection. Anti-inflammatory medicines used to reduce swelling in airways. Drugs or steroids such as azithromycin, ibuprofen, prednisone and pentoxifylline are used to reduce inflammation. For the treatment of bacterial infection various lung antibiotics such as nebcin, tobrex, ciprofloxin, myambutol, biaxin, azactam are used Exercise: Aerobic exercise can help to reduce and clear the mucus from the airways. Regular exercise also enables to cut back on the CPT. Intracytoplasmic sperm injection is used to provide fertility for men with cystic fibrosis LUNG TRANSPLANTATION: Lung transplantion is a effective therapeutic option for the cystic-fibrosis patient. The successfully lung transplanted patients are able to control diabetic problems easily as the patients exercise capacity improves and the respiratory infection reduces.(Madden, 1992). In lung transplant ,the infected lung is replaced with a healthy lung by surgery. If CF is very advanced then lung transplantion is a good option. It is a major operation and sometimes also leads to some serious complications Oxygen Therapy: If oxygen level is very low in the blood then oxygen therapy is very effective(http://cystic-fibrosis.emedtv.com). NUTRITIONAL TREATMENT: C.F causes many digestive problems such as slow growth, pain, intestinal gas and severe. Nutritional treatment can improve the growth, development and strength of patient. It involves a balanced diet with low fat and high protein which make strong the patient to resist aganist some infection (http://www.healthscout.com). It contain pancreatic enzymes to digest protein and fat and absorbance of various vitamins. Nutriational therapy also contain supplements of different vitamins. The other treatment for digestive problems is medications for the treatment of intestinal blockages (http://www.nhlbi.nih.gov/). GENE THERAPY: Gene therapy involve transfer of DNA for therapeutic purpose. For the treatment of cystic fibrosis two approaches have been used. In the first approach, adenovirus was used as a vector, it has the epithelial cell lining. In this approach, adenovirus type-2 late promoter drives the CFTR gene. In the second approach, positively charged liposomes was used which can bind negatively charged DNA on its surface. These initial experiments have been used to change the electrical conductance of the nasal membrane. By these approaches a little correction of conductance abnormalities is possible. In the recent studies aerosol inhalers is used to saturate the upper part of the respiratory system. The reversal of the path physiology is possible if the correct form of CFTR gene is expressed. At present, retroviral-mediated gene transfer system is used for gene transfer for gene therapy of CF. Adenovirus is a suitable vector for gene transfer to the airway because it uses humans as a permissive host and it has a natural tropism for the lung .Liposome-mediated DNA transfer system is also used for gene transfer in gene therapy. Liposome is positively charged interact with DNA which is negatively charged and form lipid-coated DNA complex Different positively charged liposomes used to transfer the CFTR including DOTAP, DMRIE and DOTMA-DOPE. Several new treatments are developed to treat the CF. In one case, the sodium-channel inhibitor amiloride is insert to the airways of the patients which inhibit sodium absorption. The other possible approach is to allow to bypass the CFTR chloride channel and regulate other chloride channel present in the membrane of airways. The most effective way to treat the CF is to insert a new and normal copy of CFTR gene into the airway of respiratory tract of CF patients. RECENT ADVANCES: In recent years, various research works have improved the way to diagnose and treat cystic fibrosis. In the year 2006, it was published in the Science daily that certain scientists from Stanford University, USA were able to find out the basic defect causing CF. In which they had concluded that the airway blockage caused in CF was not caused due excessive fluid being reabsorbed within the glands but due to lack of fluid secretion from cystic fibrosis glands. (http://www.sciencedaily.com/releases/2006/03/060318232035.htm) In another research work done in the year 2008, certain scientist from USA were able to discover that a particular protein called CFTR were either missing or not present in the lungs of the CF patients which helps in fighting various bacteria like Pseudomonas aeruginosa when inhaled. Further studies are conducted to find the treatment through these proteins. (http://www.sciencedaily.com/releases/2008/09/080910210525.htm). In 2010, A team led by Professor Justin Hanes from John Hopkins university had researched on a mucus penetrating biodegradable nanoparticles which would help in delivery wide range of therapeutic molecules from small to various size of macromolecules to reduce the infection of lungs of the CF patients. In another research study done this year 2010, a team of researches were able to find out that a certain calcium- activated chloride channel were able to enable CF mucous cells to secrete normally which is required in the CFTR channel. So, it was concluded that drugs should be produces to enchance the ability of the calcium response which helps in activating the calcium activated chloride channels which are secreted in the CF cells. (http://www.sciencedaily.com/releases/2010/09/100917151848.htm)

Wednesday, November 13, 2019

Semantics Essay -- Communication, Language

Language is the primary source of communication for humans and is used to convey thoughts, feelings, intentions, and desires to others (Bonvillain 2008:1). Many rules are taken into account when forming a language. According to Bolton, language is arbitrary and is unrepresentative of the objects they represent (Bolton 1996: 63). The study of Semantics allows us to identify the meaning of words and phrases in their literal sense, and helps us to make meaning out of arbitrary sounds and phrases. It has been contributed to by both linguists and philosophers. Linguists used lexical decomposition to understand the features that comprise words and the categories in which the words fit. Philosophers dealt more with the meanings of sentences and truth condition and reference (Parker and Riley 2010: 28).Semantics is still not a completely understood field, and as a result it is not easy to study (Parker and Riley 2010:26-27).Semantics is split into three different sections: sense, reference, and truth conditions. Thanks to semantics, we gain an understanding of what words mean when they are said to us. Without semantics, we would not be able to understand each other. Semantics take into account cultural, situational and environmental constructs to develop meaning in different areas of the United States and throughout the world (Bonvillain 2008: 27). With that being said, there are several things that semantics brings to the English language that allows us to communicate on a deeper level and makes our language more complex. Sense is the study of the literal and intentional meaning of words and phrases. Part of this section is lexical ambiguity. This occurs when one word has more than one meaning. Parker and Riley use the example of the wo... ...nd not in the other (Parker and Riley 2010: 40). Presuppositions are phrases that have to be considered true in order to evaluate the validity of another phrase. For example if I said â€Å"Judy Genshaft is the president of USF† and â€Å"Judy Genshaft is a good president,† you would have to accept the idea that she is the president in order to understand whether she was a good or bad president. In conclusion, semantics is what we use to make sense of our language. It takes into account the cultural references, environmental sayings, and situation events. Maybe the reason that semantics is so hard to understand is because it tries to make sense of something that has no meaning and things that change from place to place. Without it, our language would be much more primitive than it is now, but because of it we can make sense of things, make references, and understand truth.

Monday, November 11, 2019

Assess the Biomedical and Socio-Medical

This essay will assess how useful the biomedical and socio-medical models of health are and what contributions they have made to health and social care. The biomedical model of health is an approach which eliminates psychological and social factors (environment) but only comprises biological issues in trying to recognise or understand an individual’s medial illness/disorder. In the Western world, the biomedical model has dominated all other models of health since the 19th century.This model is the model of health most used by health care professionals and is the foundation of most medical science. As a result, it is the cure that doctors focus on. Their approach is based on what is perceived as normal or abnormal in terms of bodily functions. The biomedical model is most effective with short-term or acute illnesses, where a cause is identified and the relevant treatment is administered. It is least effective when dealing with chronic illnesses; those which persist over long pe riods of time and are managed rather than cured.The biomedical model of health fits in well with the functionalist perspective to sociology as it sees ill-health as being dysfunctional to society. For functionalists, if people adopt the sick role they are exempt from their usual roles and responsibilities. The biomedical model also takes a curative approach, meaning that it focusses on the cure of an illness. Focussing on physical aspects of illnesses means they can be scientifically tested, which therefore allows development of treatments. A disadvantage of the biomedical model of health is that it is not a long-term strategy.By not looking at a patient’s medical history, asking them how they feel and also not asking fully detailed questions about an illness, means that the same illness could re-occur in the future. Marxists criticise the biomedical model of health because this model ignores an individual’s living conditions and Marxists also argue that doctors only b enefit the rich by getting poor people back to good health in order to enable them to go back to work. Further criticisms of this theory are focussed principally on the suggestion that it has over-simplified the biological processes now known to be very intricate.For many diseases, there are multiple and interacting causes. Moreover, such a theory looks only to the agent of disease, and ignores the host and the possibilities of biological adaptation. As stated, this theory is much more easily applicable to acute conditions then to chronic ill-health and is difficult to apply to mental disorders. The biomedical model also cannot explain why some illnesses are more common in some social or ethnic groups, for example, schizophrenia in Afro-Caribbean people.Diseases are differently defined in different cultures and medical definitions of disease have clearly changed over time. Generally, it can be seen that what is viewed as illness in any particular society and at any historical time d epends on cultural norms and social values (Naidoo & Wills, 2004). McKeown (1979) argues that the biomedical model is â€Å"less effective† than other models because health started to improve before the NHS came into place. The socio-medical model argues that health is a complex mix of behavioural, structural, material and cultural factors. All together these impact on health.The social model emphasises the need to address the origins of ill-health, for example, instead of treating a child with asthma; treating the damp conditions that the child is living in. The social model came about in the mid-twentieth century when there was an increasing dissatisfaction with the dominant model of health offered by biomedicine. The emphasis on health as being simply the absence of disease encouraged thinking about only two categories; the health and the disease. The social model of health imbibes social constructs and relativity in its approach to health.It tends to define and redefine h ealth in a continuous manner, and views health differently between individuals, groups, times and cultures. Some supporters of the social model have written extensively about sickness having a role to play in various societies (Parsons, 1951) as this helps to determine the structure of and functionality of the society. The social model is organic and holistic rather than a reductionist, mechanical method. A mechanical system acts according to its programming, its instructions or natural laws.The social model allows for mental as well as physical health. This model also allows for more subtle discrimination of individuals who succeed in leading productive lives in spite of a physical impairment. Another disadvantage of this model is that the conception runs the risk of excessive breadth and of incorporating all of life. Thus, it does not distinguish clearly between the state of being healthy and the consequences of being healthy nor does it distinguish between health and the determin ants of health (Ewles and Simnett, 2010).The development of this social model has been accompanied among the public, by a growing enthusiasm for alternative therapies, which tend to rest on holistic theories. Gradually, these too have been integrated to some extent into the mainstream model. In order to have a comprehensive understanding of health, it is vital to look at various premises of health definition, as just one aspect may not provide a complete answer to the enquiry about our health at a particular given time.It is therefore important to consider the various aspects of health when making a judgement and decision about the health status of an individual. The socio-medical model fits in with the Marxist perspective to sociology, as it focusses on social and environmental factors. Poorer people are more likely to have poorer living conditions. Marxists argue that there are higher levels of illness in more impoverished areas. This model also fits in with current health policie s, for example, Change for Life, which encourages individuals to take more responsibility over their own health.The functionalist perspective also supports this model by stating that if people are taking more responsibility over their health, they will be able to contribute more to society. Finally, feminists such as Lesley Doyal (1995) support the socio-medical model by arguing that women are more likely to become ill because they have more roles in society than men. Doyal argues that women are likely to have a full time job and then still do the majority of the house work/childcare when they get home. A more stressful environment is likely to lead to a higher chance of illness.In conclusion, the biomedical model of health is obviously most easily defined by the absence of disease, though the model is also compatible with more positive definitions in terms of equilibrium of normal functioning. In the socio-medical model health is a positive state of wholeness and well-being associa ted with, but not entirely explained, by the absence of disease, illness or physical and mental impairment. The concepts of health and ill-health are unbalances. The absence of disease may be part of health but health is more than just the absence of disease.

Saturday, November 9, 2019

Free Essays on The Illegalization Of Abortion

The Illegalization of Abortion Many have pondered upon the meaning of abortion. The argument being that every child born should be wanted, and others who believe that every child conceived should be born (Sass vii). This has been a controversial topic for years. Many people want to be able to decide the destiny of others. Everyone in the United States is covered under the United States constitution, and under the 14th Amendment women have been given the choice of abortion. In 1973, Harry A. Blackmun wrote the majority opinion that it's a women's right to have an abortion. Roe v. Wade legalized abortion. Even though these people have been given the right, the case is not closed. Pro-life activists carry a strong argument, and continue to push their beliefs. They feel so strongly about these beliefs that violence has broken out in some known instances. Pro-choice activists, on the other hand, also carry very strong points. They believe that the child inside them is their property and it's life doesn't be until birth. In 1973, the United States Supreme Court decided that as long as the baby lived in the womb, he or she would be the property of the mother. Because of this decision almost every third baby conceived in America is killed by abortion, over one and a half million babies a year (Willke vii). Many countries have followed our decision on the abortion issue and some of these include Canada, England, and France. Other countries still believe abortion should be illegal, they include Germany, Ireland, and New Zealand. Although many believe that abortion is a women's choice, abortion should be banned because its immoral and life begins at conception. Abortion is the choice of a women whether or not she want's to receive one. Under the 14th Amendment's "personal liberty" women are given the right to receive an abortion. The 14th Amendment's concept of "personal liberty" and restriction... Free Essays on The Illegalization Of Abortion Free Essays on The Illegalization Of Abortion The Illegalization of Abortion Many have pondered upon the meaning of abortion. The argument being that every child born should be wanted, and others who believe that every child conceived should be born (Sass vii). This has been a controversial topic for years. Many people want to be able to decide the destiny of others. Everyone in the United States is covered under the United States constitution, and under the 14th Amendment women have been given the choice of abortion. In 1973, Harry A. Blackmun wrote the majority opinion that it's a women's right to have an abortion. Roe v. Wade legalized abortion. Even though these people have been given the right, the case is not closed. Pro-life activists carry a strong argument, and continue to push their beliefs. They feel so strongly about these beliefs that violence has broken out in some known instances. Pro-choice activists, on the other hand, also carry very strong points. They believe that the child inside them is their property and it's life doesn't be until birth. In 1973, the United States Supreme Court decided that as long as the baby lived in the womb, he or she would be the property of the mother. Because of this decision almost every third baby conceived in America is killed by abortion, over one and a half million babies a year (Willke vii). Many countries have followed our decision on the abortion issue and some of these include Canada, England, and France. Other countries still believe abortion should be illegal, they include Germany, Ireland, and New Zealand. Although many believe that abortion is a women's choice, abortion should be banned because its immoral and life begins at conception. Abortion is the choice of a women whether or not she want's to receive one. Under the 14th Amendment's "personal liberty" women are given the right to receive an abortion. The 14th Amendment's concept of "personal liberty" and restriction...

Wednesday, November 6, 2019

What role did women play in WWII essays

What role did women play in WWII essays Women played an important role in helping the United States come home with a victory. World War II created a surplus of positions that the women needed to fill when their fathers, husbands, brothers, or sons left to serve their country. Maureen Honey, author of Creating Rosie the Riveter, discusses the role that propaganda played in mobilizing women during the wartime efforts.1 In the book, G.I. Nightingales, Barbara Brooks Tomblin portrays the role that women played as nurses during World War II.2 The third book, American Women in World War II by Doris Weatherford, accounts for the diverse roles that women participated in, such as in industry, home front, and military.3 These three books depict the roles of women during World War II and examine the effects of World War II on their lives. Maureen Honey, the author of Creating Rosie the Riveter, earned her bachelors, masters, and PhD at Michigan State University. Her professional areas of specialty include the early twentieth-century American women writers, especially Harlem Renaissance, women in World War II, and popular culture. As a professor of womens studies and English at the University of Nebraska-Lincoln, Honey regularly teaches courses such as Images of Women in Popular Culture, Twentieth-century Women Writers, Seminars in Edith Wharton, and Diverse Women Writers 1900-1930. Honey continues to do work on women in World War II by working with some New York documentary makers on women war correspondents from that time period. Honey published an essay on feminine magazine fiction from the 1920s in a volume called Forgotten Feminisms in 2003. Honey recently published Bitter-Fruit: African American Women in World War II.4 Maureen Honeys long list of published pieces provides her with some credibility in her w ork on World War II because she has published several books that focus on women. This could also present some biases because Honey primarily foc...

Monday, November 4, 2019

Institutional investor double standards led to 'new economy' Essay

Institutional investor double standards led to 'new economy' businesses receiving near limitless funding for investment whil - Essay Example This current scenario appears to point to a deep change in the way investment institutions think with shifts from traditional approaches and a new economy. However, it is not a certainty that these new economy businesses will lead to an economic heaven. The dawn of the new economy threatens the values that were inherent in the old economy. To investors, it now seems that all companies need to be new economy businesses or no businesses at all. This has been deciphered as a challenge to all companies to move towards new economy businesses via lowering costs, redefining supplier and client relationships, as well as entry into new markets (Edison & Slok, 2011: p22). Institutional investor double standards led to ‘new economy’ businesses receiving near limitless funding for investment while ‘old economy’ companies restricted investment. This paper seeks to show how the difference in funding has distorted the corporate strategy and performance of these economies I t is obvious that strategies that were successful in the old economy are no longer successful in supporting the new economy. In the old economy, businesses relied on growth and development as currency to attract investment for companies like manufacturing with significant plant capacities (Keha & Singh, 2009: p44). Businesses defined their economy by their infrastructure and the way they could accumulate old capital like lending capacity, land, and equipment. Potential employees, therefore, followed the jobs. Due to the high outlay of capital and the planning involved, which was a long term, to establish business facilities, the communities were able to keep the economic activities that they possessed. In old the economy businesses, keeping business costs low was a vital strategy since low wage communities and minimum taxes were more competitive (Keha & Singh, 2009: p45). The oversight of companies and people were based on the notion of control and management. The employee market wa s regional with community competition also being low, as was the talent market. However, the new economy has turned the old economy strategies on its head. Talent as economic growth’s major currency has replaced manufacturing plants. This talent is fungible; it is exchangeable like currency. Talent is driven by various factors, including diversity and tolerance, as well as innovative environments. Sustainability is also more embedded in the new economy business than it was in the old economy (Keha & Singh, 2009: p52). Therefore, economic development in the new economy does not come, necessarily, at the expense of social inequity and depleted resources, unlike the old economy. The new economy businesses are founded on the recognition that success and economic competition is now determined on a global scale. While the elements of the new economy businesses are not all global, the ones that will have the greatest importance in coming years are. For instance, most of the employme nt opportunities lost in the State of Michigan have been lost to the service industry. The service sector seeks to meet local needs, employee services, as well as resident care (Keha & Singh, 2009: p52). Some reasons exist as to why investment institutions are looking towards the new economy business, as opposed to the old economy businesses. The double standards in funding have seen the new economies shift to digitization, which requires higher capital

Saturday, November 2, 2019

Ebola Essay Example | Topics and Well Written Essays - 500 words

Ebola - Essay Example Such an observation allows the authors to focus on the magnitude of risks associated with the eventual adoption of the measures that may be suggested to mitigate the possibilities of an outbreak in the region. The authors proceed to further mention of the cases that have been diagnosed within the American soil. The preparedness of the city is further weighed against that of regions such as texas, which have already registered possible outbreaks of the disease. The authors are keen to outline that the prospective address of the disease from findings its way to the communities in New York remains best considered under the description of collective efforts. In an effort that remains related towards the harmonization of the medical facilities in the city, the authors seek to consolidate the respective outfits of healthcare that are related to the city and harmonize them towards developing a steady outfit that aims at addressing the virus. In that effect, the authors propose the possible avenues upon which the detection and subsequent control of an outbreak may be considered. Their work does not place into consideration the possible effects that may be related to animals vectors. The focus is oriented on the human patients that traffic into New York from the various infected areas. Such allows for the description of their proposals as being narrowed on the control of human to human transmissions. Additionally, the prospective process of EVD detection has been mentioned intensely in their work. It is further argued that the adoption of a functional detection systems remains the ideal path upon which the address of the ailment is considered. The authors proceed to make references to experiences registered in the address of the disease in other regions. Their attention is oriented on the plight of eighty-eight patients that were being screened of the disease, with the aim of gathering the required experience